AF/LE Purified Anti-Human CD11a Antibody[R7-1]

Product Details

Clonality	Monoclonal
Isotype	Mouse IgG1, κ
Concentration	0.5mg/mL
Storage	This product can be stored at 2-8°C for 12 months. Do not freeze.
Buffer	0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Research Areas	Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroinflammation; Neuroscience
Clone No.	R7-1
Conjugation	Unconjugated

Immunogen Details

Abbre	CD11a
Synonyms	CD11A;ITGAL;Integrin alpha-L;LFA-1A
Swissprot	P20701

Related Products

Cat. No.	Product Name	Sizes
E-AB-F1211A	Purified Anti-Human CD11a Antibody[R7-1]	50μg / 500μg / 1mg
E-AB-F1211C	FITC Anti-Human CD11a Antibody[R7-1]	50μg / 500μg / 1mg
E-AB-F1211D	PE Anti-Human CD11a Antibody[R7-1]	50μg / 500μg / 1mg

Background

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).