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2-Chloro-4,6-dimethoxy-1,3,5-triazine 97%
2-Chloro-4,6-dimethoxy-1,3,5-triazine 97%
97%
Properties
Quality Level
200
assay
97%
form
solid
mp
71-74 °C (lit.)
SMILES string
COc1nc(Cl)nc(OC)n1
InChI
1S/C5H6ClN3O2/c1-10-4-7-3(6)8-5(9-4)11-2/h1-2H3
InChI key
GPIQOFWTZXXOOV-UHFFFAOYSA-N
Description
General description
2-Chloro-4,6-dimethoxy-1,3,5-triazine is a stable, yet highly reactive, peptide coupling agent. It is reported as useful coupling reagent for the purification of peptides. Catalytic amide-forming reactions of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported. Procedure for the preparation of multikilogram quantities of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported.
Application
2-Chloro-4,6-dimethoxy-1,3,5-triazine may be used in the following studies:
- The specific labeling of streptavidin by the modular method for affinity labeling (MoAL).
- The preparation of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, via reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine.
- The preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts, via reaction with various tertiary amines.
- The synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, via coupling with N-methylmorpholine in THF.
A stable, yet highly reactive, peptide coupling agent.
Packaging
5 g in glass bottle
Safety Information
Pictograms
GHS07
Signal Word
Warning
Hazard Statements
H315 – H319 – H335
Precautionary Statements
P261 – P264 – P271 – P280 – P302 + P352 – P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 – Skin Irrit. 2 – STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 – Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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