2-Chloro-4,6-dimethoxy-1,3,5-triazine 97%

97%

Properties

Quality Level

200

assay

97%

form

solid

mp

71-74??C (lit.)

SMILES string

COc1nc(Cl)nc(OC)n1

InChI

1S/C5H6ClN3O2/c1-10-4-7-3(6)8-5(9-4)11-2/h1-2H3

InChI key

GPIQOFWTZXXOOV-UHFFFAOYSA-N

Description

General description

2-Chloro-4,6-dimethoxy-1,3,5-triazine is a stable, yet highly reactive, peptide coupling agent.?It is reported as useful coupling reagent for the purification of peptides.?Catalytic amide-forming reactions of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported.?Procedure for the preparation of multikilogram quantities of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported.

Application

2-Chloro-4,6-dimethoxy-1,3,5-triazine may be used in the following studies:

• The specific labeling of streptavidin by the modular method for affinity labeling (MoAL).
• The preparation of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, via reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine.
• The preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts, via reaction with various tertiary amines.
• The synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, via coupling with?N-methylmorpholine in THF.

A stable, yet highly reactive, peptide coupling agent.

Packaging

5 g in glass bottle

Safety Information

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315 – H319 – H335

Precautionary Statements

P261 – P264 – P271 – P280 – P302 + P352 – P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 – Skin Irrit. 2 – STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 – Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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