N-Acetyl-L-cysteine

Sigma Grade, ?99% (TLC), powder

Synonym(s):LNAC, NAC

Properties

grade

Sigma Grade

Quality Level

200

assay

?99% (TLC)

form

powder

color

white to off-white

mp

106-108??C (lit.)

solubility

H₂O: 100?mg/mL (with heating)

application(s)

cell analysis

storage temp.

2-8?C

SMILES string

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

Description

Application

N-Acetyl-L-cysteine has been used to suppress oxygen-dependent hydroxyurea sensitivity in?Saccharomyces cerevisiae.?It has also been used as an antioxidant for the treatment of C2C12 murine myoblasts.

Packaging

5, 10, 25, 50, 100, 500 g in poly bottle1 kg in poly bottle

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Safety Information

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P264 – P280 – P305 + P351 + P338 – P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 – Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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