Choline chloride

?98%

Synonym(s):(2-Hydroxyethyl)trimethylammonium chloride

Properties

biological source

synthetic

Quality Level

200

assay

?98%

form

powder or crystals

technique(s)

cell culture | mammalian: suitable

color

colorless to white

mp

302-305??C (dec.) (lit.)

SMILES string

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

Description

General description

Choline chloride is the synthetic form of vitamin B4, choline and is a common poultry feed.

Application

Choline chloride has been used:

• as a substrate for measuring choline oxidase enzyme activity using fluorescence measurements
• as a component of non-physiological buffers for testing calcium based inhibition of cytochrome c oxidaseP
• as a component of perfusate solution for studying arterial pressure in jejunum samples

Packaging

500 g in poly bottle1, 5 kg in poly drum

Biochem/physiol Actions

Choline chloride treatment of radish seeds modulates phosphatidylcholine and phosphatidylethanolamine levels.?It elicits hepatoprotective effects and modulates methyl carbon based metabolic pathways.The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .

Substrates

Choline acetyltransferase substrate

Safety Information

Storage Class Code

11 – Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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