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Choline chloride
Choline chloride
≥98%
Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
Properties
biological source
synthetic
Quality Level
200
assay
≥98%
form
powder or crystals
technique(s)
cell culture | mammalian: suitable
color
colorless to white
mp
302-305 °C (dec.) (lit.)
SMILES string
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
Description
General description
Choline chloride is the synthetic form of vitamin B4, choline and is a common poultry feed.
Application
Choline chloride has been used:
- as a substrate for measuring choline oxidase enzyme activity using fluorescence measurements
- as a component of non-physiological buffers for testing calcium based inhibition of cytochrome c oxidaseP
- as a component of perfusate solution for studying arterial pressure in jejunum samples
Packaging
500 g in poly bottle
1, 5 kg in poly drum
Biochem/physiol Actions
Choline chloride treatment of radish seeds modulates phosphatidylcholine and phosphatidylethanolamine levels. It elicits hepatoprotective effects and modulates methyl carbon based metabolic pathways.
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .
Substrates
Choline acetyltransferase substrate
Safety Information
Storage Class Code
11 – Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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