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N-Acetyl-L-cysteine
N-Acetyl-L-cysteine
Sigma Grade, ≥99% (TLC), powder
Synonym(s):
LNAC, NAC
Properties
grade
Sigma Grade
Quality Level
200
assay
≥99% (TLC)
form
powder
color
white to off-white
mp
106-108 °C (lit.)
solubility
H2O: 100 mg/mL (with heating)
application(s)
cell analysis
storage temp.
2-8°C
SMILES string
CC(=O)N[C@@H](CS)C(O)=O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChI key
PWKSKIMOESPYIA-BYPYZUCNSA-N
Description
Application
N-Acetyl-L-cysteine has been used to suppress oxygen-dependent hydroxyurea sensitivity in Saccharomyces cerevisiae. It has also been used as an antioxidant for the treatment of C2C12 murine myoblasts.
Packaging
5, 10, 25, 50, 100, 500 g in poly bottle
1 kg in poly bottle
Biochem/physiol Actions
Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.
Safety Information
Pictograms
GHS07
Signal Word
Warning
Hazard Statements
Precautionary Statements
P264 – P280 – P305 + P351 + P338 – P337 + P313
Hazard Classifications
Eye Irrit. 2
Storage Class Code
13 – Non Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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